Vijay Reddy, PhD

Associate Professor
Structural Virology, Informatics and Customized Vaccine Design


B.Sc. in Mathematics, Physics and Chemistry, Sri Venkateswara University, India
M.Sc. in Chemistry, University of Hyderabad, Hyderabad, India
Ph.D. in Molecular Biophysics, Indian Institute of Science, Bangalore, India
Postdoctoral fellow, Purdue University, West Lafayette, IN
Postdoctoral Research Associate, TSRI, La Jolla, CA
Senior Research Scientist, TSRI, La Jolla, CA


2000-2007: Assistant Professor, Department of Molecular Biology
The Scripps Research Institute, La Jolla, California

2007-2020: Associate Professor, Dept. of Integrative Structural and Computational Biology
The Scripps Research Institute, La Jolla, California

2020-2022: Associate Professor of Integrative Virology, Dept. of Integrative Structural and Computational Biology
The Scripps Research Institute, La Jolla, California

Teaching and Mentoring Experience

Co-lecturer, Molecular modeling workshops, Principles of virus structure, TSRI Graduate Program

2000 – Present: Mentored undergraduate students (15), Graduates Students (4), Postdoctoral fellows (15)

Editorial and Reviewing Experience

  • Editorial Board, Computational and Structural Biotechnology Journal, 2012-present
  • Served as an ad hoc reviewer on NIH study sections, 2011, 2014, 2015
  • Served as a reviewer for various journals: PNAS, Scientific Reports, Journal of Molecular Biology, Journal of Structural Biology, Journal of Virology, Virology, Proteins,     Biopolymers, Bioinformatics.

Significant Publications

  • Reddy VS, Yu X, Barry MA. Refined Capsid Structure of Human Adenovirus D26 at 3.4 Å Resolution. Viruses. 2022;14(2). Epub 2022/02/27. doi: 10.3390/v14020414. PubMed PMID: 35216007
  • Montiel-Garcia, D., Santoyo-Rivera, N., Ho, P.T., Carrillo-Tripp, M., Brooks III, C.L., Johnson, J.E. and Reddy, V.S. VIPERdb 3.0: A structure-based data analytics platform for viral capsids Nucleic Acids Res 2021; 49(D1):D809-D816. doi: 10.1093/nar/gkaa1096. PMID: 33313778
  • Natchiar, S.K., Venkataraman, S., Mullen T-M., Nemerow, G.R. and Reddy, V.S. Revised crystal structure of human adenovirus reveals the limits on protein IX quasi-equivalence and on analyzing large macromolecular complexes. J Mol Biol 2018. PMID: 30121295; DOI: 10.1016/j.jmb.2018.08.011
  • Yu, X., Veesler, D., Campbell, M., Barry, M.E., Asturias, F., Barry, M.A. and Reddy, V.S. Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses. Sci. Adv. 3, e1602670 (2017)
  • Reddy, V.S. Application of the phase extension method in virus crystallography. Crystallogr Rev 22, 128-140 (2016).
  • Reddy VS, Natchiar SK, Stewart PL, Nemerow GR. Crystal structure of human adenovirus at 3.5 A resolution. Science 2010; 329(5995): 1071-1075.
  • Carrillo-Tripp M, Shepherd CM, Borelli IA, Venkataraman S, Lander G, Natarajan P, Johnson JE, Brooks CL, 3rd, Reddy VS. VIPERdb2: an enhanced and web API enabled relational database for structural virology. Nucleic Acids Res 2009;37(Database issue):D436-442.
  • Kumar, S., Ochoa, W., Singh, P., Hsu, C., Schneemann, A., Manchester, M., Olson, M., and Reddy, V. (2009). Tomato bushy stunt virus (TBSV), a versatile platform for polyvalent display of antigenic epitopes and vaccine design. Virology 388(1), 185-90.
  • Venkataraman, S., Reddy, S. P., Loo, J., Idamakanti, N., Hallenbeck, P. L., and Reddy, V. S. (2008). Structure of Seneca Valley Virus-001: an oncolytic picornavirus representing a new genus. Structure 16(10), 1555-61. PMC2572565

Primary Research Areas

  • Three dimensional structural analyses of viral capsids and proteins
  • Structural Bioinformatics and Homology Modeling
  • Customized Vaccine Design

Contact Information